Laboratory of Evolutionary Anthropology (Nakayama Unit),
Department of Integrated Biosciences, Graduate School of Frontier Sciences,
The University of Tokyo
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原著論文(査読有り. *は責任著者)

  1. Ishida Y, Nakayama K*. Infrared thermography unveiled the variation of brown adipose tissue thermogenesis among East Asian adults. Physiol Rep. 2025 Mar;13(6):e70279. doi: 10.14814/phy2.70279
  2. Ishida Y, Matsushita M, Yoneshiro T, Saito M, Nakayama K*. Association between thermogenic brown fat and genes under positive natural selection in circumpolar populations. J Physiol Anthropol. 2024;43(1):19. Published 2024 Aug 19. doi:10.1186/s40101-024-00368-1
  3. Ishida Y, Matsushita M, Yoneshiro T, Saito M, Fuse S, Hamaoka T, Kuroiwa M, Tanaka R, Kurosawa Y, Nishimura T, Motoi M, Maeda T, Nakayama K*. Genetic evidence for involvement of β2-adrenergic receptor in brown adipose tissue thermogenesis in humans. Int J Obes (Lond). 2024;48(8):1110-1117. doi:10.1038/s41366-024-01522-6
  4. Xia T, Nakayama K*. Signatures of adaptation in myopia-related genes on the sunlight exposure hypothesis. J Physiol Anthropol. 2023;42(1):25. Published 2023 Nov 2. doi:10.1186/s40101-023-00341-4
  5. Nishimura T*, Motoi M, Toyoshima H, et al. Endocrine, inflammatory and immune responses and individual differences in acute hypobaric hypoxia in lowlanders [published correction appears in Sci Rep. 2023 Aug 22;13(1):13682]. Sci Rep. 2023;13(1):12659. Published 2023 Aug 4. doi:10.1038/s41598-023-39894-w
  6. Niwa S, Kawabata T, Shoji K, Ogata H, Kagawa Y, Nakayama K, Yanagisawa Y, Iwamoto S, Tatsuta N, Asato K, Arima T, Yaegashi N, Nakai K. Investigation of Maternal Diet and FADS1 Polymorphism Associated with Long-Chain Polyunsaturated Fatty Acid Compositions in Human Milk. Nutrients. 2022 May 23;14(10):2160. doi: 10.3390/nu14102160. PMID: 35631303; PMCID: PMC9143760.
  7. Inaba Y, Iwamoto S, Nakayama, K*. Genome-wide DNA methylation status of Mongolians exhibits signs of cellular stress response related to their nomadic lifestyle. J Physiol Anthropol 41, 30 (2022). https://doi.org/10.1186/s40101-022-00305-0
  8. Watanabe K*, Nakayama K, Ohta S, Matsumoto A, Tsuda H, Iwamoto S. ILDR2 stabilization is regulated by its interaction with GRP78. Sci Rep. 2021 Apr 16;11(1):8414. doi: 10.1038/s41598-021-87884-7.
  9. Yoshida K, Yokota K, Kutsuwada Y, Nakayama K, Watanabe K, Matsumoto A, Miyashita H, Khor SS, Tokunaga K, Kawai Y, Nagasaki M, Iwamoto S*. Genome-Wide Association Study of Lean Nonalcoholic Fatty Liver Disease Suggests Human Leukocyte Antigen as a Novel Candidate Locus. Hepatol Commun. 2020 May 19;4(8):1124-1135. doi: 10.1002/hep4.1529.
  10. Nita R, Kawabata T*, Kagawa Y, Nakayama K, Yanagisawa Y, Iwamoto S, Kimura F, Miyazawa T, Tatsuta N, Arima T, Yaegashi N, Nakai K. Associations of erythrocyte fatty acid compositions with FADS1 gene polymorphism in Japanese mothers and infants. Prostaglandins Leukot Essent Fatty Acids. 2020 Jan;152:102031. doi: 10.1016/j.plefa.2019.102031.
  11. Nakayama K*, Inaba Y. Genetic variants influencing obesity-related traits in Japanese population. 46:298-304 2019  Ann Hum Biol. doi: 10.1080/03014460.2019.1644373.
    Boonvisut S, Yoshida K, Nakayama K, Watanabe K, Miyashita H, Iwamoto S.  Identification of deleterious rare variants in MTTP, PNPLA3, and TM6SF2 in Japanese males and association studies with NAFLD. Lipids Health Dis. 2017. 16:183
  12. Nakayama K*, Ohashi J, Watanabe K, Munkhtulga L, Iwamoto S. Evidence for Very Recent Positive Selection in Mongolians. Mol Biol Evol.  2017. 34:1936-1946Nakayama K*, Iwamoto S. An adaptive variant of TRIB2, rs1057001, is associated with higher expression levels of thermogenic genes in human subcutaneous and visceral adipose tissues J Phyiol Anthropol. 36:16 2017
  13. Nakayama K, Saito S, Watanabe K, Miyashita H, Nishijima F, Kamo Y, Tada K, Ishizuka S, Niwa T, Iwamoto S, Shimizu H*. Influence of AHRR Pro189Ala polymorphism on kidney functions. Biosci Biotech Biochem. 2017.  81:1120-1124
  14. Watanabe K*, Nakayama K, Ohta S, Tago K, Boonvisut S, Millings EJ, Fischer SG, LeDuc CA, Leibel RL, Iwamoto S. ZNF70, a novel ILDR2-interacting protein, contributes to the regulation of HES1 gene expression. Biochem Biophys Res Commun. 2016 477:712-6.

 

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